Opioids include legal prescription medications such as hydrocodone, oxycontin, and fentanyl, as well as illegal drugs such as heroin. The annual rate of opioid overdose deaths for those aged 15 to 24 years is 12.6 per 100,000 people. Teenagers who misuse substances can experience drug dependence (substance use disorder). Developmentally, adolescents are at the highest...